diff --git a/scrape/scrape_append_v2.go b/scrape/scrape_append_v2.go
index 825e56f9df..51863329a2 100644
--- a/scrape/scrape_append_v2.go
+++ b/scrape/scrape_append_v2.go
@@ -314,6 +314,11 @@ loop:
 			// Append sample to the storage.
 			ref, err = app.Append(ref, lset, st, t, val, h, fh, appOpts)
 		}
+		if err == nil {
+			if (parsedTimestamp == nil || sl.trackTimestampsStaleness) && ce != nil {
+				sl.cache.trackStaleness(ce.ref, ce)
+			}
+		}
 		sampleAdded, err = sl.checkAddError(met, exemplars, err, &sampleLimitErr, &bucketLimitErr, &appErrs)
 		if err != nil {
 			if !errors.Is(err, storage.ErrNotFound) {
@@ -321,9 +326,6 @@ loop:
 			}
 			break loop
 		}
-		if (parsedTimestamp == nil || sl.trackTimestampsStaleness) && ce != nil {
-			sl.cache.trackStaleness(ce.ref, ce)
-		}
 
 		// If series wasn't cached (is new, not seen on previous scrape) we need to add it to the scrape cache.
 		// But we only do this for series that were appended to TSDB without errors.
diff --git a/scrape/scrape_test.go b/scrape/scrape_test.go
index 49ee38f65d..5bc47133ad 100644
--- a/scrape/scrape_test.go
+++ b/scrape/scrape_test.go
@@ -3696,6 +3696,57 @@ func testScrapeLoopAppendGracefullyIfAmendOrOutOfOrderOrOutOfBounds(t *testing.T
 	require.Equal(t, 1, seriesAdded)
 }
 
+func TestScrapeLoopCreatesStaleMarkersOnOOOAppend(t *testing.T) {
+	foreachAppendable(t, func(t *testing.T, appV2 bool) {
+		testScrapeLoopCreatesStaleMarkersOnOOOAppend(t, appV2)
+	})
+}
+
+func testScrapeLoopCreatesStaleMarkersOnOOOAppend(t *testing.T, appV2 bool) {
+	appTest := teststorage.NewAppendable()
+	sl, _ := newTestScrapeLoop(t, withAppendable(appTest, appV2))
+
+	now := time.Unix(1, 0)
+	app := sl.appender()
+	_, _, _, err := app.append([]byte("metric1 1\n"), "text/plain", now)
+	require.NoError(t, err)
+	require.NoError(t, app.Commit())
+
+	metric1Calls := 0
+	// The test storage doesn't track order, so it cannot generate OOO error,
+	// we have to emulate it.
+	appTest.WithErrs(func(ls labels.Labels) error {
+		switch ls.Get(model.MetricNameLabel) {
+		case "metric1":
+			metric1Calls++
+			// Only return error on the first append, the second one will be the
+			// staleness marker.
+			if metric1Calls == 1 {
+				return storage.ErrOutOfOrderSample
+			}
+			return nil
+		default:
+			return nil
+		}
+	}, nil, nil)
+
+	now2 := time.Unix(2, 0)
+	app2 := sl.appender()
+	_, _, _, err = app2.append([]byte("metric1 2\n"), "text/plain", now2)
+	require.NoError(t, err)
+	require.NoError(t, app2.Commit())
+
+	samples := appTest.ResultSamples()
+	foundStale := false
+	for _, s := range samples {
+		if s.L.Get(model.MetricNameLabel) == "metric1" && value.IsStaleNaN(s.V) {
+			foundStale = true
+			break
+		}
+	}
+	require.True(t, foundStale, "Stale NaN marker was expected for metric1 but was not found")
+}
+
 func TestScrapeLoopOutOfBoundsTimeError(t *testing.T) {
 	foreachAppendable(t, func(t *testing.T, appV2 bool) {
 		testScrapeLoopOutOfBoundsTimeError(t, appV2)