diff --git a/include/haproxy/openssl-compat.h b/include/haproxy/openssl-compat.h
index 97a1b7e88..7b072bec8 100644
--- a/include/haproxy/openssl-compat.h
+++ b/include/haproxy/openssl-compat.h
@@ -52,6 +52,11 @@
 /* This macro is defined by the new OpenSSL 3.5.0 QUIC TLS API and it is not
  * defined by quictls.
  */
+
+#if defined(USE_QUIC) && (OPENSSL_VERSION_NUMBER < 0x30500010L)
+#error "OpenSSL 3.5 QUIC API should only be used with OpenSSL 3.5.1 version and newer"
+#endif
+
 #define HAVE_OPENSSL_QUIC
 #define SSL_set_quic_transport_params   SSL_set_quic_tls_transport_params
 #define SSL_set_quic_early_data_enabled SSL_set_quic_tls_early_data_enabled